Goblet cells are a type of cell found within pseudostratified ciliated columnar epithelium, which is a type of epithelium tissue found in the respiratory tract. Goblet cells are specialized secretory cells that produce and secrete mucus. They are found in the mucosal layer of the epithelium, and their main function is to provide a protective layer over the cells of the epithelium, trapping any foreign particles or bacteria and preventing them from entering the body.

Pseudostratified columnar epithelium

Tissue type
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Pseudostratified columnar epithelium
Blausen 0750 PseudostratifiedCiliatedColumnar.png

Illustration depicting Pseudostratified ciliated columnar epithelium.
Details
Function Epithelium
Identifiers
TH H2.00.02.0.02021
FMA 45572
Anatomical terms of microanatomy

This article is part of a series on
Epithelia
Squamous epithelial cell
Columnar epithelial cell
Cuboidal epithelial cell
Specialised epithelia
Other

A pseudostratified epithelium is a type of epithelium that, though comprising only a single layer of cells, has its cell nuclei positioned in a manner suggestive of stratified epithelia. As it
rarely occurs as squamous or cuboidal epithelia, it is usually considered synonymous with the term pseudostratified columnar epithelium.

The term pseudostratified is derived from the appearance of this epithelium in the section which conveys the erroneous (pseudo means almost or approaching) impression that there is more than one layer of cells, when in fact this is a true simple epithelium since all the cells rest on the basement membrane. The nuclei of these cells, however, are disposed at different levels, thus creating the illusion of cellular stratification. All cells are not of equal size and not all cells extend to the luminal/apical surface; such cells are capable of cell division providing replacements for cells lost or damaged.

Pseudostratified epithelia function in secretion or absorption. If a specimen looks stratified but has cilia, then it is a pseudostratified ciliated epithelium, since stratified epithelia do not have cilia. Ciliated epithelia are more common and lines the trachea, bronchi. Non-ciliated epithelia lines the larger ducts such as the ducts of parotid glands.

Examples

  • Ciliated pseudostratified columnar epithelia is the type of respiratory epithelium found in the linings of the trachea as well as other respiratory tract, which allows filtering and humidification of incoming air.
  • Non-ciliated pseudostratified columnar epithelia are located in the prostate and membranous part of male vas deferens.
  • Pseudostratified columnar epithelia with stereocilia are located in the epididymis. Stereocilia of the epididymis are not cilia because their cytoskeleton is composed of actin filaments, not microtubules. They are structurally and molecularly more similar to microvilli than to true cilia.[dubious discuss]
  • Pseudostratified columnar epithelia are found forming the straight, tubular glands of the endometrium in females. They are also found in the internal part of the ear.

Additional images

  • Cross-section of pseudostratified columnar epithelium

    Cross-section of pseudostratified columnar epithelium

  • Second cross-section of pseudostratified columnar epithelium

    Second cross-section of pseudostratified columnar epithelium

pseudostratified epithelium

Pseudostratified columnar epithelium, animated image highlights the epithelial cells, goblet cells, then underlying connective tissue

References

External links


Source: Pseudostratified columnar epithelium
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